catalog number :
MBS715901
products full name :
Rabbit anti-human Tax1-binding protein 3 polyclonal Antibody, FITC
products short name :
Tax1-binding protein 3
other names :
tax1-binding protein 3 isoform 2; Tax1-binding protein 3; tax1-binding protein 3; Tax1 (human T-cell leukemia virus type I) binding protein 3; Glutaminase-interacting protein 3; Tax interaction protein 1; TIP-1; Tax-interacting protein 1
other gene names :
TAX1BP3; TAX1BP3; TIP-1; TIP-1
uniprot entry name :
TX1B3_HUMAN
purity :
Caprylic Acid Ammonium Sulfate Precipitation
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
Western Blot (WB), ELISA (EIA)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: FITC
other info2 :
Immunogen: Recombinant human Tax1-binding protein 3 protein
products description :
May play a role in the Rho signaling pathway. May act as an inhibitor of the Wnt signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
ncbi acc num :
NP_001191627.1
ncbi gb acc num :
NM_001204698.1
ncbi mol weight :
13,735 Da
ncbi pathways :
RHO GTPase Effectors Pathway (1269509); RHO GTPases Activate Rhotekin And Rhophilins Pathway (1269520); Signal Transduction Pathway (1269379); Signaling By Rho GTPases Pathway (1269507); Wnt Signaling Pathway NetPath (198799)
uniprot summary :
TAX1BP3: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6. Protein type: Cell cycle regulation; Adaptor/scaffold. Chromosomal Location of Human Ortholog: 17p13. Cellular Component: cytoplasm; cytosol; nucleus; plasma membrane. Molecular Function: beta-catenin binding; protein binding; protein C-terminus binding. Biological Process: negative regulation of cell proliferation; negative regulation of Wnt receptor signaling pathway; Rho protein signal transduction; small GTPase mediated signal transduction; Wnt receptor signaling pathway