product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human NADH-cytochrome b5 reductase 3 polyclonal Antibody; FITC conjugated
catalog :
MBS715688
quantity :
0.1 mg
price :
235 USD
clonality :
polyclonal
host :
rabbit
conjugate :
FITC
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS715688
products type :
Antibody
products full name :
Rabbit anti-human NADH-cytochrome b5 reductase 3 polyclonal Antibody; FITC conjugated
products short name :
NADH-cytochrome b5 reductase 3
other names :
NADH-cytochrome b5 reductase 3 isoform 1; NADH-cytochrome b5 reductase 3; NADH-cytochrome b5 reductase 3; diaphorase-1; NADH-cytochrome b5 reductase 3 soluble form; NADH-cytochrome b5 reductase 3 membrane-bound form; cytochrome b5 reductase 3; Diaphorase-1Cleaved into the following 2 chains:NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form
other gene names :
CYB5R3; CYB5R3; B5R; DIA1; DIA1; B5R; Cytochrome b5 reductase
uniprot entry name :
NB5R3_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
301
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
form :
Liquid
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
Western Blot (WB), ELISA (EIA)
other info1 :
Immunogen: Recombinant human NADH-cytochrome b5 reductase 3 protein. Relevance: DIAPH1 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity). In hearing it may play a role in the regulation of actin polymerization in hair cells.
other info2 :
Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 . Conjugate: FITC conjugated
ncbi gi num :
4503327
ncbi acc num :
NP_000389.1
ncbi gb acc num :
NM_000398.6
uniprot acc num :
P00387
ncbi mol weight :
38,358 Da
ncbi pathways :
Amino Sugar And Nucleotide Sugar Metabolism Pathway 82979!!Amino Sugar And Nucleotide Sugar Metabolism Pathway 350!!Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway 906000!!Defective BTD Causes Biotidinase Deficiency Pathway 906015!!Defective CD320 Causes Methylmalonic Aciduria Pathway 906012!!Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway 906001!!Defective GIF Causes Intrinsic Factor Deficiency Pathway 906004!!Defective HLCS Causes Multiple Carboxylase Deficiency Pathway 906014!!Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway 906003!!Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway 906010
ncbi summary :
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
size :
0.1 mg
price :
235 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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