product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human D-3-phosphoglycerate dehydrogenase polyclonal Antibody; HRP conjugated
catalog :
MBS715668
quantity :
0.1 mg
price :
235 USD
clonality :
polyclonal
host :
rabbit
conjugate :
HRP
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS715668
products type :
Antibody
products full name :
Rabbit anti-human D-3-phosphoglycerate dehydrogenase polyclonal Antibody; HRP conjugated
products short name :
D-3-phosphoglycerate dehydrogenase
products name syn :
3-PGDH PGDH3 PHGDH
other names :
D-3-phosphoglycerate dehydrogenase; D-3-phosphoglycerate dehydrogenase; D-3-phosphoglycerate dehydrogenase; epididymis secretory protein Li 113; phosphoglycerate dehydrogenase
other gene names :
PHGDH; PHGDH; NLS; PDG; PGD; NLS1; PGAD; PGDH; SERA; 3PGDH; 3-PGDH; PHGDHD; HEL-S-113; PGDH3; 3-PGDH
uniprot entry name :
SERA_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
533
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
form :
Liquid
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
Western Blot (WB), ELISA (EIA)
other info1 :
Immunogen: Recombinant human D-3-phosphoglycerate dehydrogenase protein. Relevance: PHGDH or 3-phosphoglycerate dehydrogenase is an enzyme belonging to the D-isomer specific 2-hydroxyacid dehydrogenase family. It catalysis the reaction 3-phosphoglycerate + NAD+ = 3-phosphonooxypyruvate + NADH during L-serine biosynthesis. Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency). It is characterized by congenital microcephaly, psychomotor retardation and seizures.
other info2 :
Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 . Conjugate: HRP conjugated
ncbi gi num :
23308577
ncbi acc num :
NP_006614.2
ncbi gb acc num :
NM_006623.3
uniprot acc num :
O43175
ncbi mol weight :
56,651 Da
ncbi pathways :
Amino Acid Synthesis And Interconversion (transamination) Pathway 106173!!Biosynthesis Of Amino Acids Pathway 790012!!Biosynthesis Of Amino Acids Pathway 795174!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Glycine, Serine And Threonine Metabolism Pathway 82949!!Glycine, Serine And Threonine Metabolism Pathway 313!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Amino Acids And Derivatives Pathway 106169
ncbi summary :
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]
size :
0.1 mg
price :
235 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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