product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human 60S ribosomal protein L11 polyclonal Antibody, HRP conjugated
catalog :
MBS715217
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
HRP
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS715217
products type :
Antibody
products full name :
Rabbit anti-human 60S ribosomal protein L11 polyclonal Antibody, HRP conjugated
products short name :
60S ribosomal protein L11
products name syn :
CLL-associated antigen KW-12
other names :
60S ribosomal protein L11 isoform 1; 60S ribosomal protein L11; 60S ribosomal protein L11; ribosomal protein L11; CLL-associated antigen KW-12
other gene names :
RPL11; RPL11; L11; DBA7; GIG34
uniprot entry name :
RL11_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
178
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: HRP
other info2 :
Immunogen: Recombinant human 60S ribosomal protein L11 protein
ncbi gi num :
15431290
ncbi acc num :
NP_000966.2
ncbi gb acc num :
NM_000975.3
uniprot acc num :
P62913
ncbi mol weight :
20,124 Da
ncbi pathways :
Cap-dependent Translation Initiation Pathway (1268680); Cytoplasmic Ribosomal Proteins Pathway (198853); Disease Pathway (1268854); Eukaryotic Translation Elongation Pathway (1268690); Eukaryotic Translation Initiation Pathway (1268679); Eukaryotic Translation Termination Pathway (1268692); Formation Of A Pool Of Free 40S Subunits Pathway (1268681); GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway (1268686); Gene Expression Pathway (1269649); Infectious Disease Pathway (1269056)
ncbi summary :
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L5P family of ribosomal proteins. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Dec 2010]
uniprot summary :
RPL11: Binds to 5S ribosomal RNA. Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML. Defects in RPL11 are the cause of Diamond-Blackfan anemia type 7 (DBA7). DBA7 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Belongs to the ribosomal protein L5P family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Translation; Ribosomal; Nucleolus. Chromosomal Location of Human Ortholog: 1p36.1-p35. Cellular Component: cytoplasm; cytosol; membrane; nucleolus. Molecular Function: protein binding; RNA binding; rRNA binding; structural constituent of ribosome. Biological Process: cellular protein metabolic process; gene expression; mRNA catabolic process, nonsense-mediated decay; protein targeting; ribosomal large subunit assembly and maintenance; ribosomal large subunit biogenesis and assembly; rRNA processing; selenium metabolic process; selenocysteine metabolic process; SRP-dependent cotranslational protein targeting to membrane; translation; translational elongation; translational initiation; translational termination; viral infectious cycle; viral reproduction; viral transcription. Disease: Diamond-blackfan Anemia 7
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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