Rabbit anti- human Alpha-enolase polyclonal Antibody, HRP conjugated | MyBioSource MBS715010 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit anti- human Alpha-enolase polyclonal Antibody, HRP conjugated

catalog :

MBS715010

quantity :

0.05 mg

price :

160 USD

clonality :

polyclonal

host :

rabbit

conjugate :

HRP

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS715010

products type :

Antibody

products full name :

Rabbit anti- human Alpha-enolase polyclonal Antibody, HRP conjugated

products short name :

Alpha-enolase

products name syn :

2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding protein; ENO1; ENO1L1; MBPB1; MPB1

other names :

c-myc promoter-binding protein-1 isoform MBP-1; Alpha-enolase; alpha-enolase; c-myc promoter-binding protein-1; enolase 1, (alpha); 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding protein

other gene names :

ENO1; ENO1; NNE; PPH; MPB1; ENO1L1; HEL-S-17; ENO1L1; MBPB1; MPB1; NNE

uniprot entry name :

ENOA_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

341

purity :

Caprylic Acid Ammonium Sulfate Precipitation Purified

storage stability :

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

tested application :

ELISA (EIA), Wetsern Blot (WB), Immunohistochemistry (IHC)

other info1 :

Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: HRP

products description :

ENO1 encodes one of three enolase isoenzymes found in mammals; it encodes alpha-enolase, a homodimeric soluble enzyme, and also encodes a shorter monomeric structural lens protein, tau-crystallin. The two proteins are made from the same message. The full length protein, the isoenzyme, is found in the cytoplasm. The shorter protein is produced from an alternative translation start, is localized to the nucleus, and has been found to bind to an element in the c-myc promoter. A pseudogene has been identified that is located on the other arm of the same chromosome.

ncbi gi num :

319996655

ncbi acc num :

NP_001188412.1

ncbi gb acc num :

NM_001201483.1

uniprot acc num :

P06733

ncbi mol weight :

36,928 Da

ncbi pathways :

Biosynthesis Of Amino Acids Pathway (790012); Biosynthesis Of Amino Acids Pathway (795174); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); Gluconeogenesis Pathway (1269961); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (413342); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (468196); Glucose Metabolism Pathway (1269959); Glycolysis Pathway (1269960); Glycolysis (Embden-Meyerhof Pathway), Glucose = Pyruvate (413340)

ncbi summary :

This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]

uniprot summary :

ENO1: an abundant cytoplasmic enzyme with 2-phospho-D-glycerate hydro-lyase activity. A target of excess protein nitration in Alzheimer disease (AD) brain. Tau-crystallin, a structural lens protein, is produced from an alternative translation start in the enolase gene. Protein type: EC 4.2.1.11; Lyase; Transcription, coactivator/corepressor; Carbohydrate Metabolism - glycolysis and gluconeogenesis. Chromosomal Location of Human Ortholog: 1p36.2. Cellular Component: cytoplasm; cytosol; extracellular space; M band; membrane; nucleus; phosphopyruvate hydratase complex; plasma membrane. Molecular Function: DNA binding; GTPase binding; magnesium ion binding; phosphopyruvate hydratase activity; protein binding; transcription corepressor activity; transcription factor activity. Biological Process: carbohydrate metabolic process; gluconeogenesis; glucose metabolic process; negative regulation of cell growth; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; response to virus; transcription, DNA-dependent

size1 :

0.05 mg

price1 :

160 USD

size2 :

0.1 mg

price2 :

235

more info or order :

MyBioSource product webpage