catalog number :
MBS715004
products full name :
Rabbit anti-human L-lactate dehydrogenase A chain polyclonal Antibody, Biotin conjugated
products short name :
L-lactate dehydrogenase A chain
products name syn :
PIG19; LDHA; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59
other names :
L-lactate dehydrogenase A chain isoform 2; L-lactate dehydrogenase A chain; L-lactate dehydrogenase A chain; lactate dehydrogenase A; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59
other gene names :
LDHA; LDHA; LDHM; GSD11; PIG19; HEL-S-133P; LDH-A; LDH-M
uniprot entry name :
LDHA_HUMAN
purity :
Caprylic Acid Ammonium Sulfate Precipitation Purified
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Wetsern Blot (WB)
other info1 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugate: Biotin
other info2 :
Immunogen: Recombinant human L-lactate dehydrogenase A chain protein
products description :
Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:612933]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.
ncbi acc num :
NP_001128711.1
ncbi gb acc num :
NM_001135239.1
ncbi mol weight :
26,712 Da
ncbi pathways :
Central Carbon Metabolism In Cancer Pathway (1059538); Central Carbon Metabolism In Cancer Pathway (1084231); Cysteine And Methionine Metabolism Pathway (104488); Cysteine And Methionine Metabolism Pathway (103421); Glucagon Signaling Pathway (1144996); Glucagon Signaling Pathway (1158201); Glycolysis / Gluconeogenesis Pathway (82926); Glycolysis / Gluconeogenesis Pathway (287); Glycolysis And Gluconeogenesis Pathway (198814); HIF-1 Signaling Pathway (695200)
ncbi summary :
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]