product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human adaptor-related protein complex 3, beta 1 subunit polyclonal Antibody
catalog :
MBS714908
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS714908
products type :
Antibody
products full name :
Rabbit anti-human adaptor-related protein complex 3, beta 1 subunit polyclonal Antibody
products short name :
adaptor-related protein complex 3, beta 1 subunit
products name syn :
adaptor-related protein complex 3; beta 1 subunit; AP3B1; ADTB3; ADTB3A; HPS; HPS2; PE
other names :
Adaptor-related protein complex 3, beta 1 subunit; AP-3 complex subunit beta-1; AP-3 complex subunit beta-1; beta-3A-adaptin; AP-3 complex beta-3A subunit; adaptor protein complex AP-3 subunit beta-1; adaptor-related protein complex 3 subunit beta-1; clathrin assembly protein complex 3 beta-1 large chain; adaptor-related protein complex 3, beta 1 subunit; Adaptor protein complex AP-3 subunit beta-1; Adaptor-related protein complex 3 subunit beta-1; Beta-3A-adaptin; Clathrin assembly protein complex 3 beta-1 large chain
other gene names :
AP3B1; AP3B1; PE; HPS; HPS2; ADTB3; ADTB3A; ADTB3A
uniprot entry name :
AP3B1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
1094
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human AP3B1
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
23512245
ncbi acc num :
AAH38444.1
ncbi mol weight :
116,195 Da
ncbi pathways :
Clathrin Derived Vesicle Budding Pathway (119545); Golgi Associated Vesicle Biogenesis Pathway (119546); Lysosome Pathway (99052); Lysosome Pathway (96865); Membrane Trafficking Pathway (106160); Trans-Golgi Network Vesicle Budding Pathway (106165)
ncbi summary :
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
uniprot summary :
AP3B1: a subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. Mutations in AP3B1 cause defects of various cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes, and are the cause of Hermansky-Pudlak syndrome 2. Two alternatively spliced isoforms have been described. Protein type: Adaptor/scaffold; Vesicle. Chromosomal Location of Human Ortholog: 5q14.1. Cellular Component: Golgi apparatus; membrane; lysosomal membrane; clathrin coated vesicle membrane. Molecular Function: GTP-dependent protein binding; protein phosphatase binding. Biological Process: intracellular protein transport; protein targeting to lysosome; melanosome organization and biogenesis; anterograde synaptic vesicle transport; antigen processing and presentation, exogenous lipid antigen via MHC class Ib; positive regulation of NK T cell differentiation; anterograde axon cargo transport; blood coagulation. Disease: Hermansky-pudlak Syndrome 2
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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