catalog number :
MBS714853
products full name :
Rabbit anti-human glutamate receptor, ionotropic, N-methyl D-aspartate 2A polyclonal Antibody
products short name :
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
products name syn :
glutamate receptor; ionotropic; N-methyl D-aspartate 2A; GRIN2A; NMDAR2A; NR2A
other names :
Glutamate receptor, ionotropic, N-methyl D-aspartate 2A; Glutamate receptor ionotropic, NMDA 2A; glutamate receptor ionotropic, NMDA 2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor subunit 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1; glutamate receptor, ionotropic, N-methyl D-aspartate 2A; Glutamate [NMDA] receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A; NMDAR2A; NR2A; hNR2A
other gene names :
GRIN2A; GRIN2A; LKS; EPND; FESD; NR2A; GluN2A; NMDAR2A; NMDAR2A; GluN2A; NMDAR2A; NR2A; hNR2A
uniprot entry name :
NMDE1_HUMAN
reactivity :
Human, Mouse
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
other info1 :
Immunogen: Human GRIN2A
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAI43274.1
ncbi mol weight :
144,431 Da
ncbi pathways :
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway 161033!!Alcoholism Pathway 585563!!Alcoholism Pathway 587116!!Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!Alzheimers Disease Pathway 672448!!Amphetamine Addiction Pathway 547607!!Amphetamine Addiction Pathway 550546!!Amyotrophic Lateral Sclerosis (ALS) Pathway 83099!!Amyotrophic Lateral Sclerosis (ALS) Pathway 511
ncbi summary :
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]