product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human cathepsin D polyclonal Antibody
catalog :
MBS714698
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS714698
products type :
Antibody
products full name :
Rabbit anti-human cathepsin D polyclonal Antibody
products short name :
cathepsin D
products name syn :
cathepsin D; CTSD; CLN10; CPSD; MGC2311
other names :
cathepsin D preproprotein; Cathepsin D; cathepsin D; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10; epididymis secretory sperm binding protein Li 130P; cathepsin D
other gene names :
CTSD; CTSD; CPSD; CLN10; HEL-S-130P; CPSD
uniprot entry name :
CATD_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
412
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
other info1 :
Immunogen: Human CTSD
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
4503143
ncbi acc num :
NP_001900.1
ncbi gb acc num :
NM_001909.4
ncbi mol weight :
44,552 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Ceramide Signaling Pathway (138023); Collagen Degradation Pathway (730309); Degradation Of The Extracellular Matrix Pathway (576263); Direct P53 Effectors Pathway (137939); Extracellular Matrix Organization Pathway (576262); Immune System Pathway (106386); LKB1 Signaling Events Pathway (137957); Lysosome Pathway (99052); Lysosome Pathway (96865)
ncbi summary :
This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq, Jul 2008]
uniprot summary :
CTSD: Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. Consists of a light chain and a heavy chain. Belongs to the peptidase A1 family. Protein type: Autophagy; Motility/polarity/chemotaxis; Protease; EC 3.4.23.5. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: extracellular matrix; lysosomal lumen; extracellular space; lysosome; extracellular region; melanosome. Molecular Function: protein binding; aspartic-type endopeptidase activity. Biological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; antigen processing and presentation of exogenous peptide antigen via MHC class II; proteolysis. Disease: Ceroid Lipofuscinosis, Neuronal, 10
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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