catalog number :
MBS714648
products full name :
Rabbit anti-human ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 polyclonal Antibody
products short name :
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
products name syn :
ATPase; H+ transporting; lysosomal 56/58kDa; V1 subunit B1; ATP6V1B1; ATP6B1; MGC32642; RTA1B; VATB; VMA2; VPP3
other names :
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1; V-type proton ATPase subunit B, kidney isoform; V-type proton ATPase subunit B, kidney isoform; V-ATPase B1 subunit; V-ATPase subunit B 1; vacuolar proton pump 3; H+-ATPase beta 1 subunit; vacuolar proton pump, subunit 3; vacuolar proton pump subunit B 1; endomembrane proton pump 58 kDa subunit; H(+)-transporting two-sector ATPase, 58kD subunit; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1; Endomembrane proton pump 58 kDa subunit; Vacuolar proton pump subunit B 1
other gene names :
ATP6V1B1; ATP6V1B1; VATB; VMA2; VPP3; RTA1B; ATP6B1; ATP6B1; VATB; VPP3; V-ATPase subunit B 1
uniprot entry name :
VATB1_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human ATP6V1B1
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH63411.1
ncbi mol weight :
56,833 Da
ncbi pathways :
Collecting Duct Acid Secretion Pathway 147586!!Collecting Duct Acid Secretion Pathway 147560!!Disease Pathway 530764!!Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway 83102!!Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway 515!!Insulin Receptor Recycling Pathway 106438!!Iron Uptake And Transport Pathway 187191!!Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway 645267!!Metabolic Pathways 132956!!Oxidative Phosphorylation Pathway 82942
ncbi summary :
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq, Jul 2008]