product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human voltage-dependent anion channel 2 polyclonal Antibody
catalog :
MBS714555
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS714555
products type :
Antibody
products full name :
Rabbit anti-human voltage-dependent anion channel 2 polyclonal Antibody
products short name :
voltage-dependent anion channel 2
products name syn :
voltage-dependent anion channel 2; VDAC2; FLJ23841
other names :
Voltage-dependent anion channel 2; Voltage-dependent anion-selective channel protein 2; voltage-dependent anion-selective channel protein 2; outer mitochondrial membrane protein porin 2; voltage-dependent anion channel 2; Outer mitochondrial membrane protein porin 2
other gene names :
VDAC2; VDAC2; POR; VDAC-2; hVDAC2
uniprot entry name :
VDAC2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
294
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human VDAC2
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
54035063
ncbi acc num :
AAH12883.2
ncbi mol weight :
30,412 Da
ncbi pathways :
Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512); Parkinson's Disease Pathway (83098); CGMP-PKG Signaling Pathway (983748); CGMP-PKG Signaling Pathway (985584)
ncbi summary :
This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
uniprot summary :
VDAC2: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective. Interacts with hexokinases. Expressed in all tissues examined. Belongs to the eukaryotic mitochondrial porin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Channel, misc.; Mitochondrial; Membrane protein, integral. Chromosomal Location of Human Ortholog: 10q22. Cellular Component: pore complex; mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; nucleus. Molecular Function: protein binding; nucleotide binding; voltage-gated anion channel activity; porin activity. Biological Process: negative regulation of protein polymerization; transmembrane transport; anion transport
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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