product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human diaphanous homolog 1 (Drosophila) polyclonal Antibody
catalog :
MBS714432
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
Entamoeba histolytica HM-1:IMSS
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS714432
products type :
Antibody
products full name :
Rabbit anti-human diaphanous homolog 1 (Drosophila) polyclonal Antibody
products short name :
diaphanous homolog 1
products name syn :
diaphanous homolog 1 (Drosophila); DIAPH1; DFNA1; DIA1; DRF1; FLJ25265; LFHL1; hDIA1
other names :
diaphanous protein, homolog 1; Diaphanous protein, homolog 1, putative; diaphanous protein, homolog 1; Diaphanous protein, homolog 1, putative
other gene names :
EHI_118260; EHI_118260
uniprot entry name :
C4LZ08_ENTHI
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human,Mouse,Rat; Other species are not tested. Please decide the specificity by homology.
sequence length :
1176
purity :
Antigen Affinity Purified
form :
Liquid
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
app notes :
ELISA; Use at an assay dependent dilution. WB: 1:1000-1:10000 . IF: 1:10-1:100 (Recommender dilutions) . Positive WB detected in: HeLa cells, COS-7 cells, human heart tissue, human skeletal muscle tissue, NIH/3T3 cells . Positive IF detected in : HepG2 cells, Hela cells
other info1 :
Immunogen: Human DIAP1. Conjugate : Non-conjugated
other info2 :
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
products description :
Rabbit polyclonal to DIAPH1 . Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and promote cell migration By similarity. Has neurite outgrowth promoting activity By similarity. In hear cells, it may play a role in the regulation of actin polymerization in hair cells. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape
ncbi gi num :
67481361
ncbi acc num :
XP_656030.1
ncbi gb acc num :
XM_650938.2
ncbi mol weight :
130,858 Da
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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