product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human anoctamin 2 polyclonal Antibody
catalog :
MBS714387
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS714387
products type :
Antibody
products full name :
Rabbit anti-human anoctamin 2 polyclonal Antibody
products short name :
anoctamin 2
products name syn :
anoctamin 2; ANO2; C12orf3; DKFZp434P102; TMEM16B
other names :
anoctamin-2 isoform 2; Anoctamin-2; anoctamin-2; transmembrane protein 16B (eight membrane-spanning domains); anoctamin 2, calcium activated chloride channel; Transmembrane protein 16B
other gene names :
ANO2; ANO2; C12orf3; TMEM16B; C12orf3; TMEM16B
uniprot entry name :
ANO2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human ,Mouse, rat ;Other species are not tested. Please decide the specificity by homology.
sequence length :
999
purity :
Antigen affinity purification
form :
Liquid
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
app notes :
ELISA: Use at an assay dependent dilution. WB: 1:1000-1:10000 . IP: 1:200-1:1000 . IHC: 1:20-1:200 . IF: 1:10-1:100 (Recommender dilutions) . Positive WB detected in: Mouse brain tissue, HeLa cells, human brain tissue, mouse eye tissue . Positive IP detected in: Mouse brain tissue . Positive IHC detected in: Human breast cancer tissue. Positive IF detected in: HepG2 cells, Hela cells
other info1 :
Immunogen: Peptide. Conjugate : Non-conjugated
other info2 :
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
products description :
Rabbit polyclonal to ANO2 . Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be theunderlying chloride channel involved in this process. May mediate light perception amplification in retina.
ncbi gi num :
515870521
ncbi acc num :
NP_001265526.1
ncbi gb acc num :
NM_001278597.1
ncbi mol weight :
113,616 Da
ncbi pathways :
Ion Channel Transport Pathway (187193); Stimuli-sensing Channels Pathway (771568); Transmembrane Transport Of Small Molecules Pathway (106572)
ncbi summary :
ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011]
uniprot summary :
ANO2: Acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. May mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Transporter, ion channel; Membrane protein, multi-pass; Transporter. Chromosomal Location of Human Ortholog: 12p13.3. Cellular Component: nucleoplasm; nonmotile primary cilium; plasma membrane. Molecular Function: protein homodimerization activity; intracellular calcium activated chloride channel activity; protein heterodimerization activity. Biological Process: transmembrane transport
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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