catalog number :
MBS714302
products full name :
Rabbit anti-human tumor necrosis factor (ligand) superfamily, member 14 polyclonal Antibody
products short name :
tumor necrosis factor (ligand) superfamily, member 14
products name syn :
tumor necrosis factor (ligand) superfamily; member 14; TNFSF14; CD258; HVEML; LIGHT; LTg; TR2
other names :
tumor necrosis factor ligand superfamily member 14 isoform 1; Tumor necrosis factor ligand superfamily member 14; tumor necrosis factor ligand superfamily member 14; delta transmembrane LIGHT; herpesvirus entry mediator A; herpesvirus entry mediator ligand; herpesvirus entry mediator-ligand; herpes virus entry mediator ligand; ligand for herpesvirus entry mediator; tumor necrosis factor receptor-like 2; tumor necrosis factor superfamily member LIGHT; tumor necrosis factor (ligand) superfamily, member 14; Herpes virus entry mediator ligand; HVEM-L; Herpesvirus entry mediator ligand; CD_antigen: CD258Cleaved into the following 2 chains:Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form
other gene names :
TNFSF14; TNFSF14; LTg; TR2; CD258; HVEML; LIGHT; HVEML; LIGHT; HVEM-L; Herpesvirus entry mediator ligand
uniprot entry name :
TNF14_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human TNFSF14
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
NP_003798.2
ncbi gb acc num :
NM_003807.3
ncbi mol weight :
22,395 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Herpes Simplex Infection Pathway 377873!!Herpes Simplex Infection Pathway 377865!!NF-kappa B Signaling Pathway 634527
ncbi summary :
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]