catalog number :
MBS714294
products full name :
Rabbit anti-human mitochondrial trans-2-enoyl-CoA reductase polyclonal Antibody
products short name :
mitochondrial trans-2-enoyl-CoA reductase
products name syn :
mitochondrial trans-2-enoyl-CoA reductase; MECR; CGI-63; FASN2B; NRBF1
other names :
Mitochondrial trans-2-enoyl-CoA reductase; Trans-2-enoyl-CoA reductase, mitochondrial; trans-2-enoyl-CoA reductase, mitochondrial; nuclear receptor binding factor 1; mitochondrial 2-enoyl thioester reductase; homolog of yeast 2-enoyl thioester reductase; mitochondrial trans-2-enoyl-CoA reductase; Nuclear receptor-binding factor 1; HsNrbf-1; NRBF-1
other gene names :
MECR; MECR; NRBF1; CGI-63; FASN2B; NBRF1; HsNrbf-1; NRBF-1
uniprot entry name :
MECR_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human MECR
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH01419.1
ncbi mol weight :
32,228 Da
ncbi pathways :
Fatty Acid Biosynthesis Pathway (198873); Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway (413380); Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway (468246); Fatty Acid Elongation Pathway (82934); Fatty Acid Elongation Pathway (295); Fatty Acid Metabolism Pathway (868084); Fatty Acid Metabolism Pathway (878045); Metabolic Pathways (132956)
uniprot summary :
MECR: Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.3.1.38; Oxidoreductase; Lipid Metabolism - fatty acid elongation in mitochondria. Chromosomal Location of Human Ortholog: 1p35.3. Cellular Component: mitochondrion; nucleus. Molecular Function: zinc ion binding; trans-2-enoyl-CoA reductase (NADPH) activity. Biological Process: fatty acid metabolic process; fatty acid biosynthetic process