catalog number :
MBS714121
products full name :
Rabbit anti-human v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog polyclonal Antibody
products short name :
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
products name syn :
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; KIT; C-Kit; CD117; PBT; SCFR
other names :
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, isoform CRA_a; Mast/stem cell growth factor receptor Kit; mast/stem cell growth factor receptor Kit; p145 c-kit; proto-oncogene c-Kit; piebald trait protein; soluble KIT variant 1; tyrosine-protein kinase Kit; proto-oncogene tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD_antigen: CD117
other gene names :
KIT; KIT; PBT; SCFR; C-Kit; CD117; SCFR; SCFR; PBT
uniprot entry name :
KIT_HUMAN
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human KIT
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
EAX05461.1
ncbi mol weight :
46,658 Da
ncbi pathways :
Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Adaptive Immune System Pathway 366160!!C-MYB Transcription Factor Network Pathway 138073!!Cardiac Progenitor Differentiation Pathway 712094!!Constitutive PI3K/AKT Signaling In Cancer Pathway 685535!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550
ncbi summary :
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]