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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human solute carrier family 27 (fatty acid transporter), member 2 polyclonal Antibody
catalog :
MBS714049
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS714049
products type :
Antibody
products full name :
Rabbit anti-human solute carrier family 27 (fatty acid transporter), member 2 polyclonal Antibody
products short name :
solute carrier family 27 (fatty acid transporter), member 2
products name syn :
solute carrier family 27 (fatty acid transporter); member 2; SLC27A2; ACSVL1; FACVL1; FATP2; HsT17226; VLACS; VLCS; hFACVL1
other names :
solute carrier family 27 (fatty acid transporter), member 2, isoform CRA_c; Very long-chain acyl-CoA synthetase; very long-chain acyl-CoA synthetase; FATP-2; THCA-CoA ligase; fatty acid transport protein 2; long-chain-fatty-acid--CoA ligase; solute carrier family 27 member 2; very-long-chain acyl-CoA synthetase; very long-chain-fatty-acid-CoA ligase; very long-chain fatty-acid-coenzyme A ligase 1; fatty-acid-coenzyme A ligase, very long-chain 1; solute carrier family 27 (fatty acid transporter), member 2; Fatty acid transport protein 2; FATP-2; Fatty-acid-coenzyme A ligase, very long-chain 1; Long-chain-fatty-acid--CoA ligase (EC:6.2.1.3); Solute carrier family 27 member 2; THCA-CoA ligase; Very long-chain-fatty-acid-CoA ligase
other gene names :
SLC27A2; SLC27A2; VLCS; FATP2; VLACS; ACSVL1; FACVL1; hFACVL1; HsT17226; ACSVL1; FACVL1; FATP2; VLACS; VLACS; VLCS; FATP-2
uniprot entry name :
S27A2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
620
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
other info1 :
Immunogen: Human SLC27A2
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
119597792
ncbi acc num :
EAW77386.1
ncbi mol weight :
64,616 Da
ncbi pathways :
Alpha-oxidation Of Phytanate Pathway (106137); Bile Acid And Bile Salt Metabolism Pathway (106144); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); Peroxisomal Lipid Metabolism Pathway (106136); Peroxisome Pathway (131226); Peroxisome Pathway (131126); Synthesis Of Bile Acids And Bile Salts Pathway (106145)
ncbi summary :
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
uniprot summary :
SLC27A2: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes. Belongs to the ATP-dependent AMP-binding enzyme family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; EC 6.2.1.3; Ligase; Membrane protein, integral. Chromosomal Location of Human Ortholog: 15q21.2. Cellular Component: peroxisomal membrane; endoplasmic reticulum membrane; integral to peroxisomal membrane; mitochondrion; endoplasmic reticulum lumen; integral to endoplasmic reticulum membrane. Molecular Function: enzyme binding; fatty acid transporter activity; very-long-chain-fatty-acid-CoA ligase activity; phytanate-CoA ligase activity; ATP binding; receptor binding; long-chain-fatty-acid-CoA ligase activity. Biological Process: bile acid biosynthetic process; fatty acid beta-oxidation; very-long-chain fatty acid catabolic process; bile acid metabolic process; cellular lipid metabolic process; long-chain fatty acid metabolic process; fatty acid alpha-oxidation
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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