catalog number :
MBS714039
products full name :
Rabbit anti-human integrin, beta 4 polyclonal Antibody
products short name :
integrin, beta 4
products name syn :
integrin; beta 4; ITGB4; CD104
other names :
Integrin, beta 4; Integrin beta-4; integrin beta-4; GP150; CD104 antigen; integrin beta-4 subunit; integrin, beta 4; GP150; CD_antigen: CD104
other gene names :
ITGB4; ITGB4; CD104
uniprot entry name :
ITB4_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human ITGB4
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAI43739.1
ncbi mol weight :
106,779 Da
ncbi pathways :
Alpha6-Beta4 Integrin Signaling Pathway 198807!!Arrhythmogenic Right Ventricular Cardiomyopathy Pathway 672454!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 117293!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 116129!!Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway 730306!!Cell Junction Organization Pathway 160966!!Cell-Cell Communication Pathway 477132!!Collagen Formation Pathway 645288!!Dilated Cardiomyopathy Pathway 121494!!Dilated Cardiomyopathy Pathway 121285
ncbi summary :
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]