product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human deoxyribonuclease II, lysosomal polyclonal Antibody
catalog :
MBS714026
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS714026
products type :
Antibody
products full name :
Rabbit anti-human deoxyribonuclease II, lysosomal polyclonal Antibody
products short name :
deoxyribonuclease II, lysosomal
products name syn :
deoxyribonuclease II; lysosomal; DNASE2; DNASE2A; DNL; DNL2
other names :
Deoxyribonuclease II, lysosomal; Deoxyribonuclease-2-alpha; deoxyribonuclease-2-alpha; R31240_2; acid DNase; DNase II alpha; lysosomal DNase II; DNase II, lysosomal; deoxyribonuclease II alpha; deoxyribonuclease II, lysosomal; Acid DNase; Deoxyribonuclease II alpha; DNase II alpha; Lysosomal DNase II; R31240_2
other gene names :
DNASE2; DNASE2; DNL; DNL2; DNASE2A; DNASE2A; DNL2; DNase II alpha
uniprot entry name :
DNS2A_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
360
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human DNASE2
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
40807211
ncbi acc num :
AAH65209.1
ncbi mol weight :
33,615 Da
ncbi pathways :
Clathrin Derived Vesicle Budding Pathway (119545); Lysosome Pathway (99052); Lysosome Pathway (96865); Lysosome Vesicle Biogenesis Pathway (119547); Membrane Trafficking Pathway (106160); Trans-Golgi Network Vesicle Budding Pathway (106165)
ncbi summary :
This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq, Jul 2008]
uniprot summary :
DNASE2: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells. Belongs to the DNase II family. Protein type: Deoxyribonuclease; EC 3.1.22.1. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: lysosome; intracellular. Molecular Function: deoxyribonuclease II activity; DNA binding. Biological Process: erythrocyte differentiation; DNA fragmentation during apoptosis; DNA metabolic process
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!