catalog number :
MBS713995
products full name :
Rabbit anti-human Y box binding protein 2 polyclonal Antibody
products short name :
Y box binding protein 2
products name syn :
Y box binding protein 2; YBX2; CONTRIN; CSDA3; DBPC; MGC45104; MSY2
other names :
Y-box-binding protein 2; Y-box-binding protein 2; Y-box-binding protein 2; MSY2 homolog; DNA-binding protein C; germ cell specific Y-box binding protein; germ cell-specific Y-box-binding protein; Y box binding protein 2; Contrin; DNA-binding protein C; Dbpc; Germ cell-specific Y-box-binding protein; MSY2 homolog
other gene names :
YBX2; YBX2; DBPC; MSY2; CSDA3; CONTRIN; CSDA3; MSY2; Dbpc
uniprot entry name :
YBOX2_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human YBX2
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
NP_057066.2
ncbi gb acc num :
NM_015982.3
ncbi mol weight :
38,518 Da
ncbi summary :
This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15. [provided by RefSeq, Feb 2012]
uniprot summary :
YBX2: Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5 -UCCAUCA-3 with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay. Chromosomal Location of Human Ortholog: 17p13.1. Cellular Component: polysome; cytoplasm; nucleolus; nucleus. Molecular Function: ribonucleoprotein binding; mRNA 3 -UTR binding; DNA binding; translation regulator activity; chromatin binding; lipid binding. Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; translational attenuation; negative regulation of translation; mRNA stabilization; spermatogenesis; negative regulation of binding; spermatid development; oocyte development