catalog number :
MBS713883
products full name :
Rabbit anti-human A kinase (PRKA) anchor protein 1 polyclonal Antibody
products short name :
A kinase (PRKA) anchor protein 1
products name syn :
A kinase (PRKA) anchor protein 1; AKAP1; AKAP; AKAP121; AKAP149; AKAP84; D-AKAP1; MGC1807; PRKA1; SAKAP84
other names :
A-kinase anchor protein 1, mitochondrial; A-kinase anchor protein 1, mitochondrial; A-kinase anchor protein 1, mitochondrial; AKAP 149; D-AKAP-1; protein kinase A1; tudor domain containing 17; A-kinase anchor protein 149 kDa; protein kinase A anchoring protein 1; spermatid A-kinase anchor protein 84; protein phosphatase 1, regulatory subunit 43; dual-specificity A-kinase anchoring protein 1; A kinase (PRKA) anchor protein 1; A-kinase anchor protein 149 kDa; AKAP 149; Dual specificity A-kinase-anchoring protein 1; D-AKAP-1; Protein kinase A-anchoring protein 1; PRKA1; Spermatid A-kinase anchor protein 84; S-AKAP84
other gene names :
AKAP1; AKAP1; AKAP; PRKA1; AKAP84; TDRD17; AKAP121; AKAP149; D-AKAP1; PPP1R43; SAKAP84; AKAP149; PRKA1; AKAP 149; D-AKAP-1; PRKA1; S-AKAP84
uniprot entry name :
AKAP1_HUMAN
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
other info1 :
Immunogen: Human AKAP1
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
NP_003479.1
ncbi gb acc num :
NM_003488.3
ncbi mol weight :
62,921 Da
ncbi pathways :
Factors Involved In Megakaryocyte Development And Platelet Production Pathway (187196); G Protein Signaling Pathways (198849); Hemostasis Pathway (106028)
ncbi summary :
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq, Jul 2008]
uniprot summary :
AKAP1: Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane. AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; RNA-binding; Mitochondrial; Adaptor/scaffold. Chromosomal Location of Human Ortholog: 17q22. Cellular Component: mitochondrial outer membrane; membrane; mitochondrion; integral to membrane; cytosol. Molecular Function: protein binding; RNA binding. Biological Process: blood coagulation