catalog number :
MBS713816
products full name :
Rabbit anti-human tripartite motif-containing 54 polyclonal Antibody
products short name :
tripartite motif-containing 54
products name syn :
tripartite motif-containing 54; TRIM54; MURF; MURF-3; RNF30
other names :
tripartite motif-containing protein 54 isoform 1; Tripartite motif-containing protein 54; tripartite motif-containing protein 54; ring finger protein 30; tripartite motif-containing 54; muscle-specific RING finger protein 3; muscle-specific RING-finger protein 3; tripartite motif containing 54; Muscle-specific RING finger protein; MuRF; Muscle-specific RING finger protein 3; MuRF-3; MuRF3; RING finger protein 30
other gene names :
TRIM54; TRIM54; MURF; RNF30; muRF3; MURF-3; MURF; MURF3; RNF30; MuRF; MuRF-3; MuRF3
uniprot entry name :
TRI54_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human TRIM54
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
NP_115935.3
ncbi gb acc num :
NM_032546.3
ncbi mol weight :
44,833 Da
ncbi summary :
The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
uniprot summary :
TRIM54: May bind and stabilize microtubules during myotubes formation. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Ubiquitin ligase; Ligase; Ubiquitin conjugating system; EC 6.3.2.-. Chromosomal Location of Human Ortholog: 2p23.3. Cellular Component: microtubule; microtubule associated complex; Z disc. Molecular Function: signal transducer activity; zinc ion binding; microtubule binding. Biological Process: negative regulation of microtubule depolymerization; multicellular organismal development; cell differentiation; signal transduction; microtubule-based process