catalog number :
MBS713473
products full name :
Rabbit anti-human F-box and WD repeat domain containing 11 polyclonal Antibody
products short name :
F-box and WD repeat domain containing 11
products name syn :
F-box and WD repeat domain containing 11; FBXW11; BTRC2; BTRCP2; FBW1B; FBXW1B; Fbw11; Hos; KIAA0696
other names :
F-box and WD repeat domain containing 11; F-box/WD repeat-containing protein 11; F-box/WD repeat-containing protein 11; F-box protein Fbw1b; homologous to Slimb protein; F-box and WD-40 domain protein 11; F-box and WD-40 domain protein 1B; F-box/WD repeat-containing protein 1B; F-box and WD repeats protein beta-TrCP2; beta-transducin repeat-containing protein 2; F-box and WD repeat domain containing 11; F-box and WD repeats protein beta-TrCP2; F-box/WD repeat-containing protein 1B; Homologous to Slimb protein; HOS
other gene names :
FBXW11; FBXW11; Hos; BTRC2; FBW1B; Fbw11; BTRCP2; FBXW1B; BTRCP2; FBW1B; FBXW1B; KIAA0696; HOS
uniprot entry name :
FBW1B_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human FBXW11
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH26213.1
ncbi mol weight :
60,898 Da
ncbi pathways :
Activation Of NF-kappaB In B Cells Pathway 576251!!Adaptive Immune System Pathway 366160!!Antigen Processing: Ubiquitination Proteasome Degradation Pathway 366162!!Canonical Wnt Signaling Pathway 138032!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Circadian Rhythm Pathway 83084!!Circadian Rhythm Pathway 495!!Class I MHC Mediated Antigen Processing Presentation Pathway 366161!!Downstream Signaling Events Of B Cell Receptor (BCR) Pathway 576250
ncbi summary :
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008]