catalog number :
MBS713343
products full name :
Rabbit anti-human protein inhibitor of activated STAT, 2 polyclonal Antibody
products short name :
protein inhibitor of activated STAT, 2
products name syn :
protein inhibitor of activated STAT; 2; PIAS2; MGC102682; MIZ1; PIASX; PIASX-ALPHA; PIASX-BETA; SIZ2; ZMIZ4; miz
other names :
Protein inhibitor of activated STAT, 2; E3 SUMO-protein ligase PIAS2; E3 SUMO-protein ligase PIAS2; DAB2-interacting protein; zinc finger, MIZ-type containing 4; msx-interacting zinc finger protein; protein inhibitor of activated STAT X; androgen receptor-interacting protein 3; protein inhibitor of activated STAT, 2; Androgen receptor-interacting protein 3; ARIP3; DAB2-interacting protein; DIP; Msx-interacting zinc finger protein; Miz1; PIAS-NY protein; Protein inhibitor of activated STAT x; Protein inhibitor of activated STAT2
other gene names :
PIAS2; PIAS2; DIP; MIZ; MIZ1; SIZ2; ARIP3; PIASX; ZMIZ4; PIASX-BETA; PIASX-ALPHA; PIASX; ARIP3; DIP; Miz1
uniprot entry name :
PIAS2_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human PIAS2
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH15190.1
ncbi mol weight :
45,057 Da
ncbi pathways :
IL12 Signaling Mediated By STAT4 Pathway 137936!!Jak-STAT Signaling Pathway 83077!!Jak-STAT Signaling Pathway 488!!Pathways In Cancer 83105!!Small Cell Lung Cancer Pathway 83118!!Small Cell Lung Cancer Pathway 530!!Sumoylation By RanBP2 Regulates Transcriptional Repression Pathway 138029!!TGF-beta Receptor Signaling Pathway 198774!!Ubiquitin Mediated Proteolysis Pathway 83056!!Ubiquitin Mediated Proteolysis Pathway 466
ncbi summary :
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011]