catalog number : 
MBS713266
products full name : 
Rabbit anti-human endoglin polyclonal Antibody
products short name : 
endoglin
products name syn : 
endoglin; ENG; CD105; END; FLJ41744; HHT1; ORW; ORW1
other names : 
endoglin isoform 1; Endoglin; endoglin; CD105 antigen; endoglin; CD_antigen: CD105
other gene names : 
ENG; ENG; END; HHT1; ORW1; END
uniprot entry name : 
EGLN_HUMAN
reactivity : 
Human, Mouse, Rat
purity : 
Antigen Affinity Purified
tested application : 
ELISA (EIA), Western Blot (WB)
other info1 : 
Immunogen: Human ENG
other info2 : 
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num : 
NP_001108225.1
ncbi gb acc num : 
NM_001114753.2
ncbi mol weight : 
67,542 Da
ncbi pathways : 
HIF-1-alpha Transcription Factor Network Pathway  138045!!TGF Beta Signaling Pathway  198810!!TGF-beta Receptor Signaling Pathway  198774
ncbi summary : 
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]