catalog number :
MBS713042
products full name :
Rabbit anti-human cytochrome c oxidase subunit 8A (ubiquitous) polyclonal Antibody
products short name :
cytochrome c oxidase subunit 8A
products name syn :
cytochrome c oxidase subunit 8A (ubiquitous); COX8A; COX; COX8; COX8-2; COX8L; VIII; VIII-L
other names :
cytochrome c oxidase subunit 8A, mitochondrial; Cytochrome c oxidase subunit 8A, mitochondrial; cytochrome c oxidase subunit 8A, mitochondrial; cytochrome c oxidase subunit 8-2; cytochrome c oxidase subunit VIII; cytochrome c oxidase subunit 8A (ubiquitous); cytochrome c oxidase polypeptide VIII-liver/heart; cytochrome c oxidase subunit VIIIA (ubiquitous); Cytochrome c oxidase polypeptide VIII-liver/heart; Cytochrome c oxidase subunit 8-2
other gene names :
COX8A; COX8A; COX; COX8; VIII; COX8L; COX8-2; VIII-L; COX8; COX8L
uniprot entry name :
COX8A_HUMAN
reactivity :
Human,Mouse; Other species are not tested. Please decide the specificity by homology.
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ELISA: Use at an assay dependent dilution. WB : 1:1000-1:10000 . IHC : 1:20-1:200 (Recommender dilutions) . Positive WB detected in :Mouse skeletal muscle tissue, human skeletal muscle tissue . Positive IHC detected in : Human heart tissue, human hepatocirrhosis tissue
other info1 :
Immunogen: Human COX8A. Conjugate: Non-conjugated
other info2 :
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Avoid freeze / thaw cycles.
products description :
Rabbit polyclonal to COX8A . Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
ncbi acc num :
NP_004065.1
ncbi gb acc num :
NM_004074.2
ncbi mol weight :
7,579 Da
ncbi pathways :
Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Arachidonate Epoxygenase / Epoxide Hydrolase Pathway (198838); Cardiac Muscle Contraction Pathway (93344); Cardiac Muscle Contraction Pathway (93992); Cytochrome C Oxidase Pathway (413434); Cytochrome C Oxidase Pathway (468345); Electron Transport Chain Pathway (198860); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512)
ncbi summary :
The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008]
uniprot summary :
COX8A: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase VIII family. Protein type: Membrane protein, integral; Mitochondrial; Energy Metabolism - oxidative phosphorylation. Chromosomal Location of Human Ortholog: 11q12-q13. Cellular Component: mitochondrial inner membrane; integral to membrane. Molecular Function: cytochrome-c oxidase activity. Biological Process: cellular metabolic process; generation of precursor metabolites and energy; transmembrane transport