catalog number :
MBS712948
products full name :
Rabbit anti-human X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) polyclonal Antibody
products short name :
X-ray repair complementing defective repair in Chinese hamster cells 5
products name syn :
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining); XRCC5; FLJ39089; KARP-1; KARP1; KU80; KUB2; Ku86; NFIV
other names :
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining); X-ray repair cross-complementing protein 5; X-ray repair cross-complementing protein 5; TLAA; CTC85; CTCBF; nuclear factor IV; Ku autoantigen, 80kDa; DNA repair protein XRCC5; thyroid-lupus autoantigen; 86 kDa subunit of Ku antigen; lupus Ku autoantigen protein p86; Ku86 autoantigen related protein 1; CTC box-binding factor 85 kDa subunit; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining); 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
other gene names :
XRCC5; XRCC5; KU80; KUB2; Ku86; NFIV; KARP1; KARP-1; G22P2; CTC85; CTCBF; TLAA
uniprot entry name :
XRCC5_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human XRCC5
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH95442.1
ncbi mol weight :
82,705 Da
ncbi pathways :
2-LTR Circle Formation Pathway 105993!!BARD1 Signaling Events Pathway 137959!!Coregulation Of Androgen Receptor Activity Pathway 138085!!Cytosolic Sensors Of Pathogen-associated DNA Pathway 576255!!DNA Repair Pathway 105837!!DNA-PK Complex Pathway 413430!!DNA-PK Complex Pathway 890556!!Disease Pathway 530764!!Double-Strand Break Repair Pathway 105861!!Early Phase Of HIV Life Cycle Pathway 105985
ncbi summary :
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]