product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human proprotein convertase subtilisin/kexin type 7 polyclonal Antibody
catalog :
MBS712867
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS712867
products type :
Antibody
products full name :
Rabbit anti-human proprotein convertase subtilisin/kexin type 7 polyclonal Antibody
products short name :
proprotein convertase subtilisin/kexin type 7
products name syn :
proprotein convertase subtilisin/kexin type 7; PCSK7; LPC; PC7; PC8; SPC7
other names :
proprotein convertase subtilisin/kexin type 7 preproprotein; Proprotein convertase subtilisin/kexin type 7; proprotein convertase subtilisin/kexin type 7; prohormone convertase 7; proprotein convertase 7; proprotein convertase 8; prohormone convertase PC7; proprotein convertase PC7; lymphoma proprotein convertase; subtilisin/kexin-like protease PC7; proprotein convertase subtilisin/kexin type 7; Lymphoma proprotein convertase; Prohormone convertase 7; Proprotein convertase 7; PC7; Proprotein convertase 8; PC8; hPC8; Subtilisin/kexin-like protease PC7
other gene names :
PCSK7; PCSK7; LPC; PC7; PC8; SPC7; LPC; PC7; PC8; SPC7; PC7; PC8; hPC8
uniprot entry name :
PCSK7_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
785
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human PCSK7
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
20336248
ncbi acc num :
NP_004707.2
ncbi gb acc num :
NM_004716.3
ncbi mol weight :
86,247 Da
ncbi summary :
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes and plays a role in the regulation of iron metabolism. A t(11;14)(q23;q32) chromosome translocation associated with B-cell lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq, Feb 2014]
uniprot summary :
PCSK7: Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif. Belongs to the peptidase S8 family. Protein type: Protease; EC 3.4.21.-; Membrane protein, integral. Chromosomal Location of Human Ortholog: 11q23-q24. Cellular Component: integral to Golgi membrane. Molecular Function: peptidase activity; serine-type endopeptidase activity. Biological Process: peptide hormone processing; protein processing; proteolysis
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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