catalog number :
MBS712799
products full name :
Rabbit anti-human 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2 polyclonal Antibody
products short name :
6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2
products name syn :
6-phosphofructo-2-kinase/fructose-2; 6-biphosphatase 2; PFKFB2; DKFZp781D2217; MGC138308; MGC138310; PFK-2/FBPase-2
other names :
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; PFK/FBPase 2; PFKFB, cardiac; 6PF-2-K/Fru-2,6-P2ase 2; 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme; fructose-2,6-bisphosphatase, cardiac isozyme; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozymeIncluding the following 2 domains:6-phosphofructo-2-kinase (EC:2.7.1.105); Fructose-2,6-bisphosphatase (EC:3.1.3.46)
other gene names :
PFKFB2; PFKFB2; PFK-2/FBPase-2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2
uniprot entry name :
F262_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human PFKFB2
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAI12104.1
ncbi mol weight :
54,406 Da
ncbi pathways :
AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Disease Pathway 530764!!Fructose And Mannose Metabolism Pathway 82930!!Fructose And Mannose Metabolism Pathway 291!!Glucose Metabolism Pathway 106199!!Glycogen Storage Diseases Pathway 980468!!Glycolysis Pathway 105911!!HIF-1 Signaling Pathway 695200!!Metabolism Pathway 477135
ncbi summary :
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]