catalog number :
MBS712776
products full name :
Rabbit anti-human X-ray repair complementing defective repair in Chinese hamster cells 4 polyclonal Antibody
products short name :
X-ray repair complementing defective repair in Chinese hamster cells 4
products name syn :
X-ray repair complementing defective repair in Chinese hamster cells 4;
other names :
X-ray repair complementing defective repair in Chinese hamster cells 4; DNA repair protein XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4; X-ray repair, complementing defective, repair in Chinese hamster; X-ray repair complementing defective repair in Chinese hamster cells 4; X-ray repair cross-complementing protein 4
other gene names :
XRCC4; XRCC4
uniprot entry name :
XRCC4_HUMAN
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human XRCC4
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH16314.1
ncbi mol weight :
35,372 Da
ncbi pathways :
2-LTR Circle Formation Pathway 105993!!DNA Repair Pathway 105837!!Disease Pathway 530764!!Double-Strand Break Repair Pathway 105861!!Early Phase Of HIV Life Cycle Pathway 105985!!HIV Infection Pathway 105983!!HIV Life Cycle Pathway 105984!!Integration Of Provirus Pathway 105991!!Non-homologous End Joining Pathway 198895!!Non-homologous End-joining Pathway 83047
ncbi summary :
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008]