catalog number :
MBS712704
products full name :
Rabbit anti-human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 polyclonal Antibody
products short name :
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
products name syn :
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4;
other names :
dual specificity tyrosine-phosphorylation-regulated kinase 4 isoform 3; Dual specificity tyrosine-phosphorylation-regulated kinase 4; dual specificity tyrosine-phosphorylation-regulated kinase 4; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
other gene names :
DYRK4; DYRK4
uniprot entry name :
DYRK4_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human DYRK4
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
NP_001269215.1
ncbi gb acc num :
NM_001282286.1
ncbi mol weight :
59,537 Da
ncbi summary :
This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013]
uniprot summary :
DYRK4: a dual-specificity protein kinase of the DYRK family. Its expression is up-regulated by retinoic-acid-induced differentiation of a human neuronal precursor teratocarcinoma cell line. Protein type: EC 2.7.12.1; Protein kinase, CMGC; Kinase, protein; Protein kinase, dual-specificity (non-receptor); CMGC group; DYRK family; Dyrk2 subfamily. Chromosomal Location of Human Ortholog: 12p13.32. Cellular Component: intracellular membrane-bound organelle; cytoplasm; nucleus. Molecular Function: protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; metal ion binding; protein serine/threonine/tyrosine kinase activity; ATP binding. Biological Process: peptidyl-tyrosine phosphorylation