product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 polyclonal Antibody
catalog :
MBS712420
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS712420
products type :
Antibody
products full name :
Rabbit anti-human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 polyclonal Antibody
products short name :
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
products name syn :
serpin peptidase inhibitor; clade G (C1 inhibitor); member 1; SERPING1; C1IN; C1INH; C1NH; HAE1; HAE2
other names :
Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Plasma protease C1 inhibitor; plasma protease C1 inhibitor; serpin G1; C1-inhibiting factor; C1 esterase inhibitor; complement component 1 inhibitor; serine/cysteine proteinase inhibitor clade G member 1; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1
other gene names :
SERPING1; SERPING1; C1IN; C1NH; HAE1; HAE2; C1INH; C1IN; C1NH; C1 Inh; C1Inh
uniprot entry name :
IC1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
500
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human SERPING1
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
15029894
ncbi acc num :
AAH11171.1
ncbi mol weight :
55,769 Da
ncbi pathways :
Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Formation Of Fibrin Clot (Clotting Cascade) Pathway (106057); Hemostasis Pathway (106028); Intrinsic Pathway (106059); Pertussis Pathway (218111); Pertussis Pathway (218099); Platelet Activation, Signaling And Aggregation Pathway (106034); Platelet Degranulation Pathway (106050)
ncbi summary :
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, Jul 2008]
uniprot summary :
SERPING1: a protein protease inhibitor (C1-inhibitor) that forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play an important role in regulating complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Mutations of the SERPING1 gene is associated with adult macular degeneration can also cause hereditary angioedema. Binds to E.coli stcE which allows localization of SERPING1 to cell membranes thus protecting the bacteria against complement-mediated lysis. Belongs to the serpin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11q12.1. Cellular Component: extracellular space; extracellular region. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding. Biological Process: negative regulation of complement activation, lectin pathway; platelet activation; fibrinolysis; platelet degranulation; blood circulation; innate immune response; blood coagulation; blood coagulation, intrinsic pathway; complement activation, classical pathway; aging. Disease: Complement Component 4, Partial Deficiency Of; Angioedema, Hereditary, Type I
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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