catalog number :
MBS712352
products full name :
Rabbit anti-human X-linked Kx blood group (McLeod syndrome) polyclonal Antibody
products short name :
X-linked Kx blood group
products name syn :
X-linked Kx blood group (McLeod syndrome); XK; KX; X1k; XKR1
other names :
X-linked Kx blood group (McLeod syndrome); Membrane transport protein XK; membrane transport protein XK; Kx antigen; neurocanthocytosis; neuroacanthocytosis; XK-related protein 1; kell complex 37 kDa component; Kell blood group precursor (McLeod phenotype); XK, Kell blood group complex subunit (McLeod syndrome); X-linked Kx blood group; Kell complex 37 kDa component; Kx antigen; XK-related protein 1
other gene names :
XK; XK; KX; NA; NAC; X1k; XKR1; MCLDS; XKR1; XRG1
uniprot entry name :
XK_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human XK
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH36019.1
ncbi mol weight :
50,902 Da
ncbi summary :
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008]
uniprot summary :
XK: May be involved in sodium-dependent transport of neutral amino acids or oligopeptides. Defects in XK are the cause of McLeod syndrome (MLS). It is an X-linked multisystem disorder characterized by late onset abnormalities in the neuromuscular and hematopoietic systems. Belongs to the XK family. Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: Xp21.1. Cellular Component: integral to membrane. Molecular Function: protein binding; transporter activity. Biological Process: cellular calcium ion homeostasis; myelination; transport; amino acid transport; regulation of axon diameter; skeletal muscle fiber development; regulation of cell size. Disease: Mcleod Syndrome