catalog number :
MBS712139
products full name :
Rabbit anti-human matrix metallopeptidase 14 (membrane-inserted) polyclonal Antibody
products short name :
matrix metallopeptidase 14
products name syn :
matrix metallopeptidase 14 (membrane-inserted); MMP14; MMP-X1; MT1-MMP; MTMMP1
other names :
matrix metallopeptidase 14 (membrane-inserted), isoform CRA_b; Matrix metalloproteinase-14; matrix metalloproteinase-14; membrane type 1 metalloprotease; membrane-type-1 matrix metalloproteinase; matrix metallopeptidase 14 (membrane-inserted); MMP-X1; Membrane-type matrix metalloproteinase 1; MT-MMP 1; MTMMP1; Membrane-type-1 matrix metalloproteinase; MT1-MMP; MT1MMP
other gene names :
MMP14; MMP14; MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1; MMP-14; MT-MMP 1; MTMMP1; MT1-MMP; MT1MMP
uniprot entry name :
MMP14_HUMAN
reactivity :
Human, Mouse, Rat, Zebrafish
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human MMP14
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
EAW66237.1
ncbi mol weight :
65,894 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!Activation Of Matrix Metalloproteinases Pathway 576264!!Collagen Degradation Pathway 730309!!Degradation Of The Extracellular Matrix Pathway 576263!!Extracellular Matrix Organization Pathway 576262!!GnRH Signaling Pathway 83091!!GnRH Signaling Pathway 502!!HIF-2-alpha Transcription Factor Network Pathway 137956!!Matrix Metalloproteinases Pathway 198900!!Senescence And Autophagy Pathway 198780
ncbi summary :
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]