product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human phosphatidylethanolamine binding protein 1 polyclonal Antibody
catalog :
MBS712074
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS712074
products type :
Antibody
products full name :
Rabbit anti-human phosphatidylethanolamine binding protein 1 polyclonal Antibody
products short name :
phosphatidylethanolamine binding protein 1
products name syn :
phosphatidylethanolamine binding protein 1; PEBP1; HCNP; PBP; PEBP; RKIP
other names :
Phosphatidylethanolamine binding protein 1; Phosphatidylethanolamine-binding protein 1; phosphatidylethanolamine-binding protein 1; neuropolypeptide h3; prostatic binding protein; prostatic-binding protein; raf kinase inhibitor protein; Raf kinase inhibitory protein; epididymis luminal protein 210; epididymis secretory protein Li 34; hippocampal cholinergic neurostimulating peptide; phosphatidylethanolamine binding protein 1; HCNPpp; Neuropolypeptide h3; Prostatic-binding protein; Raf kinase inhibitor protein; RKIP
other gene names :
PEBP1; PEBP1; PBP; HCNP; PEBP; RKIP; HCNPpp; PEBP-1; HEL-210; HEL-S-34; PBP; PEBP; PEBP-1; RKIP; HCNP
uniprot entry name :
PEBP1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
187
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human PEBP1
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
21410340
ncbi acc num :
AAH31102.1
ncbi mol weight :
21,057 Da
ncbi pathways :
Aurora B Signaling Pathway (138080); EGFR1 Signaling Pathway (198782); ErbB1 Downstream Signaling Pathway (138057); TNF-alpha/NF-kB Signaling Pathway (198884)
ncbi summary :
This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in neural development. This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Jul 2015]
uniprot summary :
RKIP: a metastasis suppressor that regulates extracellular matrix remodeling and tumor survival. Binds to and inhibits Raf-1. Phosphorylation by classic and atypical but not novel PKC isoforms dissociates this complex, relieving inhibition of the Raf/MAP kinase signaling cascade. Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. Cleaved into hippocampal cholinergic neurostimulating peptide (HCMP) that appears to be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Expressed in brain. Increased expression in aged senescence-accelerated mice. Protein type: Lipid-binding; Protein kinase, regulatory subunit. Chromosomal Location of Human Ortholog: 12q24.23. Cellular Component: cytoplasm; nucleus. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; enzyme binding; phosphatidylethanolamine binding; protein kinase binding; ATP binding
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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