catalog number :
MBS711914
products full name :
Rabbit anti-human splicing factor, arginine/serine-rich 17A polyclonal Antibody
products short name :
splicing factor, arginine/serine-rich 17A
products name syn :
splicing factor; arginine/serine-rich 17A; SFRS17A; 721P; CCDC133; CXYorf3; DXYS155E; MGC125365; MGC125366; MGC39904; XE7; XE7Y
other names :
Splicing factor, arginine/serine-rich 17A; A-kinase anchor protein 17A; A-kinase anchor protein 17A; pseudoautosomal gene XE7; B-lymphocyte surface antigen; protein kinase A-anchoring protein 17A; splicing factor, arginine/serine-rich 17A; A kinase (PRKA) anchor protein 17A; 721P; B-lymphocyte antigen; Protein XE7; Protein kinase A-anchoring protein 17A; PRKA17A; Splicing factor, arginine/serine-rich 17A
other gene names :
AKAP17A; AKAP17A; XE7; 721P; XE7Y; CCDC133; CXYorf3; PRKA17A; SFRS17A; AKAP-17A; DXYS155E; CXYorf3; DXYS155E; SFRS17A; XE7; AKAP-17A; PRKA17A
uniprot entry name :
AK17A_HUMAN
reactivity :
Human; Other species are not tested. Please decide the specificity by homology.
purity :
Antigen Affinity Purified
storage stability :
Shipped at 4 degree C Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
ELISA: Use at an assay dependent dilution. WB : 1:500-1:5000 . IP : 1:200-1:2000 . IHC : 1:20-1:200 . IF : 1:10-1:100 (Recommender dilutions). Positive WB detected in: Human kidney tissue, human heart tissue . Positive IP detected in: Jurkat cells . Positive IHC detected in: Human pancreas cancer tissue. Positive IF detected in: HT-1080 cells
other info1 :
Immunogen: Human SFRS17A. Conjugate : Non-conjugated
other info2 :
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
products description :
Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.
ncbi acc num :
AAI10497.1
ncbi summary :
This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010]
uniprot summary :
SFRS17A: Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre- mRNA splicing in a PKA-dependent manner. 3 isoforms of the human protein are produced by alternative splicing. Protein type: RNA splicing. Chromosomal Location of Human Ortholog: Xp22.33 and Yp11.32. Cellular Component: nucleoplasm; spliceosome; cytoplasm; nuclear speck; nucleus. Molecular Function: protein binding; protein kinase A binding; nucleotide binding. Biological Process: B cell activation; regulation of transcription, DNA-dependent; regulation of RNA splicing; RNA splicing; signal transduction; mRNA processing