catalog number :
MBS711806
products full name :
Rabbit anti-human uroplakin 2 polyclonal Antibody
products short name :
uroplakin 2
products name syn :
uroplakin 2; UPK2; MGC138598; UP2; UPII
other names :
uroplakin-2; Uroplakin-2; uroplakin-2; uroplakin II; uroplakin 2; Uroplakin II; UPII
other gene names :
UPK2; UPK2; UP2; UPII; UP2; UPII
uniprot entry name :
UPK2_HUMAN
reactivity :
Human,Mouse,Rat; Other species are not tested. Please decide the specificity by homology.
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA; Use at an assay dependent dilution. WB : 1:200-1:2000 . IHC : 1:20-1:200 (Recommender dilutions). Positive WB detected in: Mouse testis tissue, mouse kidney tissue . Positive IHC detected in: Human bladder tissue
other info1 :
Immunogen: Human UPK2. Conjugate : Non-conjugated
other info2 :
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
products description :
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM.
ncbi acc num :
NP_006751.1
ncbi gb acc num :
NM_006760.3
ncbi mol weight :
19,438 Da
ncbi summary :
This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009]
uniprot summary :
UPK2: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM. Belongs to the uroplakin-2 family. Protein type: Membrane protein, integral; Endoplasmic reticulum. Chromosomal Location of Human Ortholog: 11q23. Cellular Component: integral to plasma membrane; apical plasma membrane; integral to endoplasmic reticulum membrane. Biological Process: epithelial cell differentiation; multicellular organismal development