product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human U2 small nuclear RNA auxiliary factor 1 polyclonal Antibody
catalog :
MBS711751
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS711751
products type :
Antibody
products full name :
Rabbit anti-human U2 small nuclear RNA auxiliary factor 1 polyclonal Antibody
products short name :
U2 small nuclear RNA auxiliary factor 1
products name syn :
U2 small nuclear RNA auxiliary factor 1; U2AF1; DKFZp313J1712; FP793; RN; RNU2AF1; U2AF35; U2AFBP
other names :
U2 small nuclear RNA auxiliary factor 1; Splicing factor U2AF 35 kDa subunit; splicing factor U2AF 35 kDa subunit; splicing factor U2AF 35kDa subunit; U2 small nuclear RNA auxillary factor 1; U2 snRNP auxiliary factor small subunit; U2(RNU2) small nuclear RNA auxiliary factor binding protein; U2 small nuclear ribonucleoprotein auxillary factor, 35-KD subunit; U2 small nuclear RNA auxiliary factor 1; U2 auxiliary factor 35 kDa subunit; U2 small nuclear RNA auxiliary factor 1; U2 snRNP auxiliary factor small subunit
other gene names :
U2AF1; U2AF1; RN; FP793; U2AF35; U2AFBP; RNU2AF1; U2AF35; U2AFBP
uniprot entry name :
U2AF1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
240
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human U2AF35
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
12804941
ncbi acc num :
AAH01923.1
ncbi mol weight :
19,715 Da
ncbi pathways :
Cleavage Of Growing Transcript In The Termination Region Pathway (106560); Gene Expression Pathway (105937); Processing Of Capped Intron-Containing Pre-mRNA Pathway (160950); RNA Polymerase II Transcription Pathway (106557); RNA Polymerase II Transcription Termination Pathway (106559); Shigellosis Pathway (83104); Spliceosome Pathway (125136); Spliceosome Pathway (124832); Transport Of Mature Transcript To Cytoplasm Pathway (105959); Transport Of Mature MRNA Derived From An Intron-Containing Transcript Pathway (105960)
ncbi summary :
This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
uniprot summary :
U2AF1: Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3 -splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron. Belongs to the splicing factor SR family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: RNA-binding; RNA splicing; Spliceosome; RNA processing. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: nucleoplasm; Cajal body; spliceosome; nuclear speck. Molecular Function: protein binding; RS domain binding; metal ion binding; nucleotide binding. Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA export from nucleus; RNA splicing; gene expression; mRNA 3 -end processing; mRNA processing; termination of RNA polymerase II transcription
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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