product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human lysophosphatidylcholine acyltransferase 1 polyclonal Antibody
catalog :
MBS711659
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS711659
products type :
Antibody
products full name :
Rabbit anti-human lysophosphatidylcholine acyltransferase 1 polyclonal Antibody
products short name :
lysophosphatidylcholine acyltransferase 1
products name syn :
lysophosphatidylcholine acyltransferase 1; LPCAT1; AYTL2; FLJ12443; FLJ41609; PFAAP3; lpcat
other names :
lysophosphatidylcholine acyltransferase 1; Lysophosphatidylcholine acyltransferase 1; lysophosphatidylcholine acyltransferase 1; LPCAT-1; lysoPAFAT; LPC acyltransferase 1; acyltransferase like 2; acyltransferase-like 2; lysoPC acyltransferase 1; lyso-PAF acetyltransferase; regulated by phosphonoformate; acetyl-CoA:lyso-PAF acetyltransferase; phosphonoformate immuno-associated protein 3; 1-acylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; acyl-CoA:lysophosphatidylcholine acyltransferase 1; acetyl-CoA:lyso-platelet-activating factor acetyltransferase; lysophosphatidylcholine acyltransferase 1; 1-acylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase (EC:2.3.1.67); Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; Acetyl-CoA:lyso-PAF acetyltransferase; Lyso-PAF acetyltransferase; LysoPAFAT; Acyltransferase-like 2; Phosphonoformate immuno-associated protein 3
other gene names :
LPCAT1; LPCAT1; AYTL2; lpcat; PFAAP3; AYTL2; PFAAP3; LPC acyltransferase 1; LPCAT-1; LysoPC acyltransferase 1; Acetyl-CoA:lyso-PAF acetyltransferase; Lyso-PAF acetyltransferase; LysoPAFAT
uniprot entry name :
PCAT1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human,Mouse,Rat; Other species are not tested. Please decide the specificity by homology.
sequence length :
534
purity :
Antigen Affinity Purified
form :
Liquid
storage stability :
Shipped at 4 degree C Upon delivery aliquot and store at -20 degree C or -80 degreeC. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
app notes :
ELISA:Use at an assay dependent dilution. WB : 1:1000-1:10000. IP : 1:1000-1:10000. IHC : 1:20-1:200. IF : 1:10-1:100(Recommender dilutions). Positive WB detected in: Human lung tissue, mouse brain tissue, mouse lung tissue, mouse spleen tissue, rat brain tissue, rat lung tissue. Positive IP detected in: Mouse brain tissue . Positive IHC detected in: Human colon cancer tissue, human lung cancer tissue. Positive IF detected in: MCF-7 cells
other info1 :
Immunogen: Human LPCAT1. Conjugate : Non-conjugated
other info2 :
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
products description :
Rabbit polyclonal to LPCAT1 . Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-independent. Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology.
ncbi gi num :
33946291
ncbi acc num :
NP_079106.3
ncbi gb acc num :
NM_024830.3
ncbi pathways :
Acyl Chain Remodelling Of PC Pathway (645321); Acyl Chain Remodelling Of PG Pathway (645328); Ether Lipid Metabolism Pathway (82990); Ether Lipid Metabolism Pathway (365); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Glycerophospholipid Biosynthesis Pathway (645313); Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364); Metabolic Pathways (132956); Metabolism Pathway (477135)
ncbi summary :
Lysophosphatidylcholine (LPC) acyltransferase (LPCAT; EC 2.3.1.23) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis (Nakanishi et al., 2006 [PubMed 16704971]).[supplied by OMIM, May 2008]
uniprot summary :
LPCAT1: Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-independent. Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. Protein type: Membrane protein, integral; EC 2.3.1.23; EC 2.3.1.67; Acetyltransferase; Endoplasmic reticulum. Chromosomal Location of Human Ortholog: 5p15.33. Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane; lipid particle. Molecular Function: 1-alkylglycerophosphocholine O-acetyltransferase activity; 1-alkenylglycerophosphocholine O-acyltransferase activity; 1-acylglycerophosphocholine O-acyltransferase activity; 1-alkylglycerophosphocholine O-acyltransferase activity; calcium ion binding. Biological Process: retina development in camera-type eye; phospholipid metabolic process; glycerophospholipid biosynthetic process; positive regulation of protein catabolic process; phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; surfactant homeostasis; phospholipid biosynthetic process
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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