catalog number :
MBS711503
products full name :
Rabbit anti-human bone morphogenetic protein receptor, type IA polyclonal Antibody
products short name :
bone morphogenetic protein receptor, type IA
products name syn :
bone morphogenetic protein receptor; type IA; BMPR1A; 10q23del; ACVRLK3; ALK3; CD292; SKR5
other names :
Bone morphogenetic protein receptor, type IA; Bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor type-1A; ALK-3; BMPR-1A; BMP type-1A receptor; activin receptor-like kinase 3; activin A receptor, type II-like kinase 3; serine/threonine-protein kinase receptor R5; bone morphogenetic protein receptor, type IA; Activin receptor-like kinase 3; ALK-3; Serine/threonine-protein kinase receptor R5; SKR5; CD_antigen: CD292
other gene names :
BMPR1A; BMPR1A; ALK3; SKR5; CD292; ACVRLK3; 10q23del; ACVRLK3; ALK3; BMP type-1A receptor; BMPR-1A; ALK-3; SKR5
uniprot entry name :
BMR1A_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human BMPR1A
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH28383.1
ncbi mol weight :
60,198 Da
ncbi pathways :
BMP Signalling And Regulation Pathway 198910!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Endochondral Ossification Pathway 198812!!Heart Development Pathway 198802!!Hippo Signaling Pathway 749777!!Hippo Signaling Pathway 750388!!Integrated Breast Cancer Pathway 219801!!Signal Transduction Pathway 477114!!Signaling By BMP Pathway 106336
ncbi summary :
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]