product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human solute carrier family 27 (fatty acid transporter), member 4 polyclonal Antibody
catalog :
MBS711481
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS711481
products type :
Antibody
products full name :
Rabbit anti-human solute carrier family 27 (fatty acid transporter), member 4 polyclonal Antibody
products short name :
solute carrier family 27 (fatty acid transporter), member 4
products name syn :
solute carrier family 27 (fatty acid transporter); member 4; SLC27A4; ACSVL4; FATP4
other names :
Solute carrier family 27 (fatty acid transporter), member 4; Long-chain fatty acid transport protein 4; long-chain fatty acid transport protein 4; solute carrier family 27 (fatty acid transporter), member 4; Solute carrier family 27 member 4
other gene names :
SLC27A4; SLC27A4; IPS; FATP4; ACSVL4; ACSVL4; FATP4; FATP-4; Fatty acid transport protein 4
uniprot entry name :
S27A4_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
643
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human SLC27A4
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
40675396
ncbi acc num :
AAH65003.1
ncbi mol weight :
26,001 Da
ncbi pathways :
Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Fatty Acids Pathway (187185); Transport Of Vitamins, Nucleosides, And Related Molecules Pathway (161075)
ncbi summary :
This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome. [provided by RefSeq, Apr 2010]
uniprot summary :
SLC27A4: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. Defects in SLC27A4 are the cause of ichthyosis prematurity syndrome (IPS). A keratinization disorder characterized by complications in the second trimester of pregnancy resulting from polyhydramnion, with premature birth of a child with thick caseous desquamating epidermis, respiratory complications and transient eosinophilia. After recovery during the first months of life, the symptoms are relatively benign and the patients suffer from a lifelong non-scaly ichthyosis with atopic manifestations. Belongs to the ATP-dependent AMP-binding enzyme family. Protein type: Transporter, SLC family; Membrane protein, integral; Ligase; EC 6.2.1.-; Transporter; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 9q34.11. Cellular Component: endoplasmic reticulum membrane; microvillus; membrane; brush border membrane; plasma membrane; integral to membrane. Molecular Function: fatty acid transporter activity; nucleotide binding; very-long-chain-fatty-acid-CoA ligase activity; long-chain-fatty-acid-CoA ligase activity. Biological Process: skin development; long-chain fatty acid transport; very-long-chain fatty acid catabolic process; transport; long-chain fatty acid metabolic process; lipid metabolic process; medium-chain fatty acid transport; transmembrane transport; fatty acid transport; response to nutrient. Disease: Ichthyosis Prematurity Syndrome
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!