Rabbit anti-human colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) polyclonal Antibody | MyBioSource MBS711361 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit anti-human colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) polyclonal Antibody

catalog :

MBS711361

quantity :

0.05 mL

price :

375 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS711361

products type :

Antibody

products full name :

Rabbit anti-human colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) polyclonal Antibody

products short name :

colony stimulating factor 2 receptor, alpha, low-affinity

products name syn :

colony stimulating factor 2 receptor; alpha; low-affinity (granulocyte-macrophage); CSF2RA; CD116; CDw116; CSF2R; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM-CSF-R-alpha; GMCSFR; GMR; MGC3848; MGC4838

other names :

Colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GMR-alpha; GMCSFR-alpha; CD116 antigen; GM-CSF receptor alpha subunit; colony stimulating factor 2 receptor alpha subunit; granulocyte-macrophage colony-stimulating factor receptor alpha chain; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); CDw116; CD_antigen: CD116

other gene names :

CSF2RA; CSF2RA; GMR; CD116; CSF2R; SMDP4; CDw116; CSF2RX; CSF2RY; GMCSFR; CSF2RAX; CSF2RAY; GM-CSF-R-alpha; CSF2R; CSF2RY; GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha

uniprot entry name :

CSF2R_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human; Other species are not tested. Please decide the specificity by homology.

sequence length :

400

purity :

Antigen Affinity Purified

form :

Liquid

storage stability :

Shipped at 4 degree C Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

ELISA: Use at an assay dependent dilution. WB : 1:200-1:2000. IHC : 1:20-1:200 Recommender dilutions) . Positive WB detected in:HepG2 cells, human placenta tissue . Positive IHC detected in: Human placenta tissue

other info1 :

Immunogen: Human CSF2RA. Conjugate: Non-conjugated

other info2 :

Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

products description :

Rabbit polyclonal to CSF2RA . Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.

ncbi gi num :

12803601

ncbi acc num :

AAH02635.1

ncbi pathways :

Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Immune System Pathway (106386); Interleukin Receptor SHC Signaling Pathway (187095); Interleukin-2 Signaling Pathway (205110); Interleukin-3, 5 And GM-CSF Signaling Pathway (187094); Jak-STAT Signaling Pathway (83077)

ncbi summary :

The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008]

uniprot summary :

CSF2RA: Low affinity receptor for granulocyte-macrophage colony- stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4). A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Belongs to the type I cytokine receptor family. Type 5 subfamily. 8 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, cytokine. Chromosomal Location of Human Ortholog: Xp22.32 and Yp11.3. Cellular Component: integral to plasma membrane; plasma membrane; extracellular region. Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; receptor activity. Biological Process: response to ethanol; cytokine and chemokine mediated signaling pathway. Disease: Surfactant Metabolism Dysfunction, Pulmonary, 4

size1 :

0.05 mL

price1 :

375 USD

size2 :

0.15 mL

price2 :

715

more info or order :

MyBioSource product webpage