catalog number :
MBS711019
products full name :
Rabbit anti-human adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 polyclonal Antibody
products short name :
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
products name syn :
adaptor protein; phosphotyrosine interaction; PH domain and leucine zipper containing 1; APPL1; APPL; DIP13alphaDIP13A
other names :
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; DCC-interacting protein 13-alpha; DCC-interacting protein 13-alpha; dip13-alpha; AKT2 interactor; signaling adaptor protein DIP13alpha; adapter protein containing PH domain, PTB domain and leucine zipper motif 1; adaptor protein containing pH domain, PTB domain and leucine zipper motif 1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; Adapter protein containing PH domain, PTB domain and leucine zipper motif 1
other gene names :
APPL1; APPL1; APPL; DIP13alpha; ; Dip13-alpha
uniprot entry name :
DP13A_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human APPL1
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH28599.1
ncbi mol weight :
79,663 Da
ncbi pathways :
Apoptosis Pathway 105648!!Colorectal Cancer Pathway 83106!!Colorectal Cancer Pathway 518!!Coregulation Of Androgen Receptor Activity Pathway 138085!!EGFR1 Signaling Pathway 198782!!FSH Signaling Pathway 672455!!Pathways In Cancer 83105!!Regulation Of Apoptosis Pathway 105685!!Role Of DCC In Regulating Apoptosis Pathway 161011
ncbi summary :
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]