product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human Rho GDP dissociation inhibitor (GDI) gamma polyclonal Antibody
catalog :
MBS710991
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS710991
products type :
Antibody
products full name :
Rabbit anti-human Rho GDP dissociation inhibitor (GDI) gamma polyclonal Antibody
products short name :
Rho GDP dissociation inhibitor (GDI) gamma
products name syn :
Rho GDP dissociation inhibitor (GDI) gamma; ARHGDIG; RHOGDI-3
other names :
Rho GDP dissociation inhibitor (GDI) gamma; Rho GDP-dissociation inhibitor 3; rho GDP-dissociation inhibitor 3; rho GDI 3; RhoGDI gamma; rho-GDI gamma; Rho GDP dissociation inhibitor (GDI) gamma; Rho-GDI gamma
other gene names :
ARHGDIG; ARHGDIG; RHOGDI-3; Rho GDI 3
uniprot entry name :
GDIR3_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse,Rat; Other species are not tested. Please decide the specificity by homology.
sequence length :
225
purity :
Antigen Affinity Purified
form :
Liquid
storage stability :
Shipped at 4 degree C Upon delivery aliquot and store at -20 degree Cor -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ELISA: Use at an assay dependent dilution. WB: 1:500-1:5000. IHC: 1:50-1:200(Recommender dilutions). Positive WB detected in: HeLa cells, HEK-293 cells, human brain tissue, MCF-7 cells. Positive IHC detected in: Human pancreas cancer tissue
other info1 :
Immunogen: Human ARHGDIG. Conjugate: Non-conjugated
other info2 :
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
products description :
Rabbit polyclonal to ARHGDIG . Function: Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP-and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.
ncbi gi num :
28839701
ncbi acc num :
AAH47699.1
ncbi pathways :
G13 Signaling Pathway (198800); Neurotrophin Signaling Pathway (101143); Neurotrophin Signaling Pathway (100064); Regulation Of RhoA Activity Pathway (138070); Rho GTPase Cycle Pathway (106503); Signal Transduction Pathway (477114); Signaling By Rho GTPases Pathway (106502); Vasopressin-regulated Water Reabsorption Pathway (143700); Vasopressin-regulated Water Reabsorption Pathway (143631)
ncbi summary :
The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).[supplied by OMIM, Nov 2010]
uniprot summary :
RhoGDI gamma: Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post- translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP. Belongs to the Rho GDI family. Protein type: Inhibitor; Motility/polarity/chemotaxis; G protein regulator, misc.; Cell adhesion. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: membrane; cytoplasmic membrane-bound vesicle; cytosol. Molecular Function: Rho GDP-dissociation inhibitor activity; GTPase activator activity. Biological Process: regulation of small GTPase mediated signal transduction; regulation of protein localization; small GTPase mediated signal transduction; negative regulation of cell adhesion; Rho protein signal transduction; positive regulation of GTPase activity
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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