catalog number :
MBS710931
products full name :
Rabbit anti-human lamin B receptor polyclonal Antibody
products short name :
lamin B receptor
products name syn :
lamin B receptor; LBR; DHCR14B; FLJ43126; LMN2R; MGC9041; PHA
other names :
lamin B receptor; Lamin-B receptor; lamin-B receptor; tudor domain containing 18; integral nuclear envelope inner membrane protein; lamin B receptor; Integral nuclear envelope inner membrane protein; LMN2R
other gene names :
LBR; LBR; PHA; LMN2R; TDRD18; DHCR14B
uniprot entry name :
LBR_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human LBR
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAA59494.1
ncbi mol weight :
70,703 Da
ncbi pathways :
Cholesterol Biosynthesis Pathway 106142!!Gastric Cancer Network 2 Pathway 760637!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!Cholesterol Biosynthesis I Pathway 142267!!Cholesterol Biosynthesis I Pathway 138627!!Cholesterol Biosynthesis II (via 24,25-dihydrolanosterol) Pathway 142266!!Cholesterol Biosynthesis II (via 24,25-dihydrolanosterol) Pathway 138626!!Cholesterol Biosynthesis III (via Desmosterol) Pathway 142268!!Cholesterol Biosynthesis III (via Desmosterol) Pathway 138628
ncbi summary :
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]