product summary
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company name :
MyBioSource
product type :
antibody
product name :
SRRM4 Antibody
catalog :
MBS7108916
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
MyBioSource MBS7108916 image 1
Western Blot. Positive WB detected in: Rat kidney tissue, Mouse lung tissue. All lanes: SRRM4 antibody at 4.2ug/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 69 KDa. Observed band size: 69 KDa.
image 2 :
MyBioSource MBS7108916 image 2
IHC image of MBS7108916 diluted at 1:500 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 degree C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
product information
catalog number :
MBS7108916
products type :
Antibody
products full name :
SRRM4 Antibody
products short name :
[SRRM4]
products name syn :
[Serine/arginine repetitive matrix protein 4 (Medulloblastoma antigen MU-MB- 2.76) (Neural-specific serine/arginine repetitive splicing factor of 100 kDa) (Neural-specific SR-related protein of 100 kDa) (nSR100), SRRM4, KIAA1853]
other names :
[serine/arginine repetitive matrix protein 4; Serine/arginine repetitive matrix protein 4; serine/arginine repetitive matrix protein 4; serine/arginine repetitive matrix 4; Medulloblastoma antigen MU-MB-2.76; Neural-specific serine/arginine repetitive splicing factor of 100 kDa; Neural-specific SR-related protein of 100 kDa; nSR100]
products gene name :
[SRRM4]
other gene names :
[SRRM4; SRRM4; nSR100; KIAA1853; MU-MB-2.76; KIAA1853; Neural-specific SR-related protein of 100 kDa; nSR100]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
611
purity :
>95%, Protein G purified
form :
Liquid
storage stability :
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:5000. IHC: 1:500-1:1000
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Conjugation: Non-conjugated. Research Area: Epigenetics and Nuclear Signaling. Immunogen: Recombinant Human Serine/arginine repetitive matrix protein 4 protein (400-479AA). Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
products categories :
Epigenetics and Nuclear Signaling; Cell biology; Developmental biology
products description :
Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (By similarity).
ncbi gi num :
50083281
ncbi acc num :
NP_919262.2
ncbi gb acc num :
NM_194286.3
uniprot acc num :
A7MD48
ncbi summary :
SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009 [PubMed 19737518]).[supplied by OMIM, Oct 2009]
uniprot summary :
Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts ().
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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