catalog number :
MBS7108916
products full name :
SRRM4 Antibody
products short name :
[SRRM4]
products name syn :
[Serine/arginine repetitive matrix protein 4 (Medulloblastoma antigen MU-MB- 2.76) (Neural-specific serine/arginine repetitive splicing factor of 100 kDa) (Neural-specific SR-related protein of 100 kDa) (nSR100), SRRM4, KIAA1853]
other names :
[serine/arginine repetitive matrix protein 4; Serine/arginine repetitive matrix protein 4; serine/arginine repetitive matrix protein 4; serine/arginine repetitive matrix 4; Medulloblastoma antigen MU-MB-2.76; Neural-specific serine/arginine repetitive splicing factor of 100 kDa; Neural-specific SR-related protein of 100 kDa; nSR100]
products gene name :
[SRRM4]
other gene names :
[SRRM4; SRRM4; nSR100; KIAA1853; MU-MB-2.76; KIAA1853; Neural-specific SR-related protein of 100 kDa; nSR100]
reactivity :
Human, Mouse, Rat
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:5000. IHC: 1:500-1:1000
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Conjugation: Non-conjugated. Research Area: Epigenetics and Nuclear Signaling. Immunogen: Recombinant Human Serine/arginine repetitive matrix protein 4 protein (400-479AA). Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
products categories :
Epigenetics and Nuclear Signaling; Cell biology; Developmental biology
products description :
Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (By similarity).
ncbi acc num :
NP_919262.2
ncbi gb acc num :
NM_194286.3
ncbi summary :
SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009 [PubMed 19737518]).[supplied by OMIM, Oct 2009]
uniprot summary :
Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts ().