product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human brevican polyclonal Antibody
catalog :
MBS710876
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig s5m
Liddelow S, Guttenplan K, Clarke L, Bennett F, Bohlen C, Schirmer L, et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. 2017;541:481-487 pubmed publisher
product information
catalog number :
MBS710876
products type :
Antibody
products full name :
Rabbit anti-human brevican polyclonal Antibody
products short name :
brevican
products name syn :
brevican; BCAN; BEHAB; CSPG7; MGC13038
other names :
brevican core protein isoform 1; Brevican core protein; brevican core protein; chondroitin sulfate proteoglycan 7; chondroitin sulfate proteoglycan BEHAB; brain-enriched hyaluronan-binding protein; brevican; Brain-enriched hyaluronan-binding protein; BEHAB; Chondroitin sulfate proteoglycan 7
other gene names :
BCAN; BCAN; BEHAB; CSPG7; BEHAB; CSPG7; BEHAB
uniprot entry name :
PGCB_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
911
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human BCAN
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
38372935
ncbi acc num :
NP_068767.3
ncbi gb acc num :
NM_021948.4
ncbi mol weight :
71,671 Da
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); CS/DS Degradation Pathway (645311); Chondroitin Sulfate Biosynthesis Pathway (645309); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Degradation Of The Extracellular Matrix Pathway (576263); Dermatan Sulfate Biosynthesis Pathway (645310); Disease Pathway (530764); ECM Proteoglycans Pathway (833812); Extracellular Matrix Organization Pathway (576262); Glycogen Storage Diseases Pathway (980468)
ncbi summary :
This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
uniprot summary :
BCAN: May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. Belongs to the aggrecan/versican proteoglycan family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 1q31. Cellular Component: proteinaceous extracellular matrix; lysosomal lumen; Golgi lumen; extracellular region. Molecular Function: extracellular matrix structural constituent; hyaluronic acid binding; carbohydrate binding. Biological Process: extracellular matrix organization and biogenesis; central nervous system development; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; hippocampus development; pathogenesis; dermatan sulfate biosynthetic process; chondroitin sulfate metabolic process; extracellular matrix disassembly; chondroitin sulfate catabolic process; carbohydrate metabolic process; cell adhesion; skeletal development
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!