catalog number :
MBS7107859
products full name :
EPX Antibody
products short name :
[EPX]
products name syn :
[Eosinophil peroxidase; EPO; Eosinophil peroxidase light chainEosinophil peroxidase heavy chain; EPX; EPER; EPO; EPP]
other names :
[eosinophil peroxidase preproprotein; Eosinophil peroxidase; eosinophil peroxidase; eosinophil peroxidase]
products gene name :
[EPX]
other gene names :
[EPX; EPX; EPO; EPP; EPXD; EPX-PEN; EPER; EPO; EPP; EPO]
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:200-1:500
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant Human Eosinophil peroxidase protein (140-300AA)
other info2 :
Conjugation: Non-conjugated. Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Species: Human. Research Area: Stem Cells
products categories :
Cancer; Metabolism; Stem cells
products description :
Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis.
ncbi acc num :
NP_000493.1
ncbi gb acc num :
NM_000502.5
ncbi summary :
This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Feb 2016]
uniprot summary :
Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis.