antibody

Rabbit anti-human actin, alpha, cardiac muscle 1 polyclonal Antibody

MBS710763

0.05 mL

375 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, ELISA, enzyme immunoassay

Antibody

Rabbit anti-human actin, alpha, cardiac muscle 1 polyclonal Antibody

actin, alpha, cardiac muscle 1

actin; alpha; cardiac muscle 1; ACTC1; ACTC; CMD1R; CMH11

actin, alpha cardiac muscle 1 proprotein; Actin, alpha cardiac muscle 1; actin, alpha cardiac muscle 1; actin, alpha, cardiac muscle 1; Alpha-cardiac actin

ACTC1; ACTC1; ACTC; ASD5; CMD1R; CMH11; LVNC4; ACTC

ACTC_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat

377

Antigen Affinity Purified

ELISA (EIA), Western Blot (WB)

Immunogen: Human ACTC1

Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.

4885049

NP_005150.1

NM_005159.4

42,019 Da

Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Cardiac Progenitor Differentiation Pathway (712094); Cardiac Muscle Contraction Pathway (93344); Cardiac Muscle Contraction Pathway (93992); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); Hypertrophic Cardiomyopathy (HCM) Pathway (114229); Hypertrophic Cardiomyopathy (HCM) Pathway (106591); Myometrial Relaxation And Contraction Pathways (198759)

Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]

ACTC1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family. Protein type: Motility/polarity/chemotaxis; Myosin-binding; Contractile; Cell development/differentiation; Cytoskeletal. Chromosomal Location of Human Ortholog: 15q14. Cellular Component: I band; extracellular space; sarcomere; focal adhesion; membrane; cytoplasm; actin filament; cytosol. Molecular Function: myosin binding; ATPase activity; ATP binding. Biological Process: response to drug; apoptosis; actin filament-based movement; muscle thin filament assembly; metabolic process; actomyosin structure organization and biogenesis; cardiac myofibril assembly; muscle filament sliding; response to ethanol; heart contraction; cardiac muscle morphogensis; actin-myosin filament sliding; cardiac muscle contraction; negative regulation of apoptosis. Disease: Cardiomyopathy, Familial Hypertrophic, 11; Atrial Septal Defect 5; Cardiomyopathy, Dilated, 1r

0.05 mL

375 USD

0.15 mL

715