catalog number :
MBS710568
products full name :
Rabbit anti-human actin related protein 2/3 complex, subunit 1B, 41kDa polyclonal Antibody
products short name :
actin related protein 2/3 complex, subunit 1B
products name syn :
actin related protein 2/3 complex; subunit 1B; 41kDa; ARPC1B; ARC41; p40-ARC; p41-ARC
other names :
actin-related protein 2/3 complex subunit 1B; Actin-related protein 2/3 complex subunit 1B; actin-related protein 2/3 complex subunit 1B; arp2/3 complex 41 kDa subunit; ARP2/3 protein complex subunit p41; actin related protein 2/3 complex, subunit 1B, 41kDa; Arp2/3 complex 41 kDa subunit; p41-ARC
other gene names :
ARPC1B; ARPC1B; ARC41; p40-ARC; p41-ARC; ARC41
uniprot entry name :
ARC1B_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human ARPC1B
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
NP_005711.1
ncbi gb acc num :
NM_005720.3
ncbi mol weight :
40,950 Da
ncbi pathways :
B Cell Receptor Signaling Pathway 198909!!Bacterial Invasion Of Epithelial Cells Pathway 149807!!Bacterial Invasion Of Epithelial Cells Pathway 148661!!CDC42 Signaling Events Pathway 137994!!ErbB1 Downstream Signaling Pathway 138057!!Fc Gamma R-mediated Phagocytosis Pathway 114228!!Fc Gamma R-mediated Phagocytosis Pathway 106590!!Pathogenic Escherichia Coli Infection Pathway 83103!!Pathogenic Escherichia Coli Infection Pathway 672459!!Pathogenic Escherichia Coli Infection Pathway 516
ncbi summary :
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011]